Fantasy managers often make the mistake of assuming that a running back selected in the early rounds of the NFL draft automatically vaults to the top of the team’s depth chart and, thus, becomes statistically relevant. While there is generally an expectation of immediate volume for the highest of the first-round selections — and we have seen this in recent seasons with Saquon Barkley, Leonard Fournette and Christian McCaffrey — after that, anything goes. Teams simply do what they desire, often with little reasoning, and fantasy managers waste their draft picks.
Source: Does Edwards-Helaire top rookie RB rankings for 2020 fantasy football drafts?
LSU Football Report 